Molecular Methods
Nucleic acid-based technologies to detect and quantify DNA, RNA, and gene expression, including tissue mRNA analysis, biodistribution of nucleic acid-based therapeutics, and ddPCR- and qPCR-based approaches.
Service
Bioanalytical Services
Analytical support integrating molecular, protein-, and cell-based methods for biologics, mRNA therapeutics, vaccines, and translational research, from early discovery to advanced preclinical studies.
Integrated Platform
We provide bioanalytical services supporting biologics, mRNA therapeutics, vaccines, and translational research projects. Our platform combines complementary molecular, protein-, and cell-based methods:
Protein- and Cell-Based Methods
Immunological, biochemical, and cellular technologies to measure protein levels, antibody responses, immune cell function, and biomarkers, including ELISA, multiplex cytokine analysis, and ELISpot.
Study Integration
Reproducible, study-specific workflows across a broad range of biological matrices and species, from rodents and large animals to non-GLP clinical samples. Available standalone or combined with in vivo studies.
Gene Expression Studies
Gene expression analysis for biologics, mRNA therapeutics, and translational research. Molecular and cellular technologies are combined to quantify nucleic acids, detect biomarkers, and profile tissue-specific expression in preclinical studies.
Technologies
Applications
- Gene Expression Profiling
- Biomarker Screening
- Copy Number Variation
- Tissue RNA Analysis
mRNA Therapeutics
Analytical workflows for mRNA therapeutics and vaccines, from biodistribution studies to immune profiling. Molecular, protein-, and cell-based assays evaluate expression, pharmacodynamics, and biological activity in preclinical models.
Technologies
Applications
- mRNA Biodistribution
- PK/PD Studies
- Immune Profiling
- Transgene Expression Analysis
Protein Quantification
Quantification of proteins, antibodies, and signaling pathways for biologics development, biomarker research, and translational studies. Reproducible platforms allow detection and monitoring across a broad range of biological matrices.
Technologies
Applications
- Biomarker Analysis
- Target Engagement
- Antibody Characterization
- Protein Expression Analysis
Cytokine Analysis
Multiplex cytokine analysis to characterize inflammatory and immune responses in preclinical and translational studies. Protein- and RNA-based approaches quantify cytokines, immune activation markers, and tissue-specific inflammatory profiles.
Technologies
Applications
- Serum Cytokine Analysis
- Tissue Cytokine mRNA Quantification
- Inflammatory Profiling
- Immune Activation Studies
Vaccine Development
Preclinical vaccination studies and analytical support for vaccine research, with particular expertise in mRNA-based platforms. The service covers characterization of humoral and cellular immune responses for vaccine optimization, efficacy assessment, and proof-of-concept studies.
Technologies
Applications
- Antibody Titer Analysis
- T-Cell Response Analysis
- Neutralization Assays
- Splenocyte Analysis
- Prime & Boost Cytokine Profiling
Luciferase-Based Analytical Methods
Reporter-based assessment of biodistribution, transgene expression, and functional activity of mRNA and gene therapy candidates. In vivo and in vitro approaches allow longitudinal monitoring and quantitative assessment of reporter gene activity.
Technologies
Applications
- in vivo Bioluminescence Imaging
- ex vivo Organ Imaging
- Luciferase DNA/RNA Quantification
- Functional Activity Assays
Interested in our bioanalytical services?
Tell us what you need and we will prepare a quote for your project.