Technology
Luminescence Imaging
Visualize biological processes directly in vivo. As an agile CRO, we offer tailored 2D optical bioluminescence imaging (BLI) to non-invasively and semi-quantitatively evaluate your compounds and disease models even in a longitudinal context. By utilizing the Andor iKon-M water-cooled, highly light-sensitive CCD camera, we achieve an outstanding signal-to-noise ratio. We combine this superior hardware with smart data analysis, delivering precise and reliable results.
Applications
| Application | Description |
|---|---|
| Biodistribution & Drug Delivery | Semi-quantitative tracking of delivery systems (such as LNPs, viral vectors, or biologics) to assess their in vivo localization, target accumulation, functional reporter gene expression, and clearance. |
| Cell Tracking (e.g., CAR-T, Stem Cells) | Semi-quantitative observation of the survival, migration, and proliferation of transplanted therapeutic cells within the host organism over time. |
| Gene Expression & Promoter Activity | Evaluating specific genetic responses, such as inflammation or tissue repair markers, using luminescent reporter systems directly in vivo. |
| Infectious Disease Progression | Visualizing the spread, tissue tropism, and eradication of luminescently tagged bacterial or viral pathogens during antimicrobial efficacy studies. |
| Oncology & Tumor Modeling | Longitudinal tracking of tumor growth, metastasis formation, and therapeutic response using luciferase-expressing cancer cell lines in living models. |
Key Features
- Agile & Custom-Tailored Study Design
- Outstanding Signal-to-Noise Ratio
- Non-Invasive Longitudinal Tracking
- Deep-Tissue Detection Capability
- Publication-Ready Visuals & Datasets