Analytical Support for mRNA Therapeutics
Comprehensive analytical testing suite for mRNA candidates, covering lipid nanoparticle characterization, encapsulation efficiency, biodistribution, and in-vivo translation readouts.
Download comprehensive service overviews, assay packages, and platform specifications for our in-vivo and bioanalytical capabilities.
Quantitative molecular, protein, and immunological assays for drug discovery and biologics characterization.
Comprehensive analytical testing suite for mRNA candidates, covering lipid nanoparticle characterization, encapsulation efficiency, biodistribution, and in-vivo translation readouts.
High-sensitivity protein quantification methodologies including capillary Western blotting (Jess) and automated immunoassay platforms for complex biological matrices.
Multiplexed cytokine, chemokine, and inflammatory biomarker profiling across serum, plasma, and tissue homogenates using electrochemiluminescence (MSD) and ELISA.
Quantitative gene expression analysis with digital droplet PCR (ddPCR) and bDNA assays for absolute target quantification without standard curve dependency.
Quantitative bioluminescence reporter assays for in-vitro promoter activation, viral vector transduction efficiency, and in-vivo optical tracking.
End-to-end bioanalytical support for novel vaccine candidates, including humoral antibody titers, cellular ELISpot assays, and adjuvant tracking.
In-vivo study protocols for biodistribution, pharmacokinetics, pharmacodynamics, and efficacy in disease models.
Quantitative organ and tissue distribution assessments for nucleic acids, viral vectors, nanoparticles, and antibodies using ddPCR, imaging, and bioanalytical readouts.
Pharmacokinetic and pharmacodynamic study designs in rodent and large animal models to define exposure, clearance, half-life, and biomarker response profiles.
Subcutaneous and orthotopic syngeneic and xenograft tumor models combined with serial blood sampling, tumor growth kinetics, and drug exposure analyses.
Platform specifications and qualified technical workflows across bio-layer interferometry and micro-CT imaging.
Label-free Bio-Layer Interferometry for real-time kinetic determination (Kon, Koff, KD) and high-throughput screening directly from crude cell extracts.
High-resolution 3D micro-computed tomography for non-destructive structural analysis, bone morphometry, and soft-tissue contrast imaging in preclinical models.
Domain-specific testing packages for specialized biological modalities including hematology and hemostasis.
Specialized in-vivo bleeding models, coagulation parameter profiling, platelet function assays, and hemophilia study designs.
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