Humoral Readouts
Antibody titers and neutralization assays to evaluate the magnitude of the humoral immune response.
Modality
mRNA Vaccines
The use of Messenger RNA (mRNA) has revolutionized medical research in recent years. Made globally famous by the rapid and successful development of COVID-19 vaccines, this innovative technology offers enormous potential that goes far beyond fighting pandemics. We support the development of your mRNA therapies and vaccines through professionally conducted in vivo studies. Our experienced team ensures the highest scientific quality combined with strict animal welfare standards.
Flexible Study Regimens
We establish and execute a wide variety of prime-boost regimens in mice, tailored exactly to your study design. Multiple boost applications can also be seamlessly implemented.
Standard Application Routes
We routinely utilize i.d. (intradermal), i.v. (intravenous), i.m. (intramuscular), and s.c. (subcutaneous) routes for the administration of test substances. Non-standard routes are available on request.
Precise Monitoring & Analytics
We perform both intermediate and final blood sampling for the detailed determination of cytokine levels and antibody titers.
Efficient and Rapid Execution
We understand that time is a critical factor in drug development. Within the framework of regulatory approvals, we guarantee a prompt realization of your projects. You will benefit from very short lead times from the initial study inquiry to the completion of the study and the handover of comprehensive study reports.
Customer Satisfaction and Animal Welfare Compliance
At preclinics we have dedicated study directors to handle your requests and studies. These contacts are available throughout the lifecycle of your project to guarantee seamless communication. Animal welfare is our top priority. All applications and blood sampling procedures are conducted in accordance with current GV-SOLAS guidelines — particularly regarding maximum blood withdrawal volumes and recovery periods.
Humoral and Cellular Readouts
Cellular Readouts
T-cell response profiling with ELISpot and flow cytometry for antigen-specific cytokine secretion.
Prime/Boost Kinetics
Cytokine profiling and longitudinal immunogenicity mapping across multiple time points.