Modality
Antibodies & ADCs
We have broad experience in both the development and analysis of antibodies and antibody-drug conjugates (ADCs). Whether exploiting natural effector functions, conjugating to reporters, or loading them with effector molecules, we help our customers maximize the high specificity and affinity of these critical biologics for both therapeutic and diagnostic applications.
Immunization Services
- Immunization programs in rabbits, chickens, and New World camelids (NWC, llamas/alpacas)
- Humanized rodents LamaMice for the generation of humanized antibodies and VHH
- Cattle immunization for antibodies with ultralong CDR3 loops
- Polyclonal antibodies from goats, sheep or chickens with protein A/G or antigen-specific affinity purification
Single-domain Antibodies (sdAb, VHH)
- Dedicated expertise in the generation of single-domain antibodies
- VHH for research, therapeutic development and diagnostic applications
Discovery Technologies
- Phage, yeast and CIS display
- NGS-based repertoire analysis
- Custom library generation
- Hybridoma development
Functional Characterization
- Affinity, cross-reactivity, and special binding condition testing
- EC50 determination across a wide range of in vitro assays
- Mammalian receptor reporter cell lines for functional assays
- In vivo PK/PD relationship analysis using SPF animal facilities
Each service can be booked individually or combined into a customized discovery program. Talk to us about your target and we will propose a suitable strategy.